crisscrosslinkeR

A package for analyzing protein-protein and protein-RNA interactions.


Introduction



crisscrosslinkeR helps to optimize XL-MS and RBDmap analysis to manage a large number of repeats with easy-to-use functions in R.


In conjunction with visualization tools such as xiNET and PyMOL, crisscrosslinkeR can help to streamline your ability to create intuitive, colorful, and informative graphics suitable for publication.


Read more about the data generated by the lab that was used in some of the tutorials here.


Installation



The package is currently available for download via GitHub. If you are unfamiliar with installing directly from GitHub, please enter the following commands in your RStudio console:

library("devtools")
install_github("egmg726/crisscrosslinker")

Documentation



You can read the full documentation here. However, we recommend going through the tutorials/workflows first. Please note that the documentation is currently under construction and will updated soon.


Workflows



Protein-Protein Interactions

Features

  • Data reduction of XL-MS repeats
  • BLAST integration and interactive menus within R
  • Alignment to UniProt and PDB files
  • Export for xiNET and PyMOL visualizations

  • Tutorials

    Protein-RNA Interactions

    Gallery